Prof. Dr Dominik Obrist - Thrombolysis in Coronary Microvascular Obstruction
Coronary microvascular obstruction (MVO) is an injury of the myocardial microcirculation. It typically follows successful recanalization of the blocked coronary artery (primary occlusion) in myocardial infarction. MVO leads to under-perfusion of the affected tissue and negatively impacts patient outcome. Next to other occluding factors, MVO may be caused by microthrombi (debris from the primary occlusion) embolizing vessels of less than 200μm diameter.